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Thermal Effect of a Woolen Cap in
Low Birthweight Infants during Kangaroo Care

Introduction

Globally, 5.8 million children younger than 5 years died in 2015, including 2.6 million neonatal deaths.[1] This burden is especially relevant in sub-Saharan Africa and Southern Asia, which accounts for most of these deaths.[2] Despite overall improvements since 1990, the reduction of neonatal mortality in low-resource countries has been slower than the reduction of maternal and child mortality.[3,4] The day of birth and the early postnatal period are the most vulnerable phases for both mother and neonate.[5,6]
Overall, it is estimated that 15% to 20% of all births worldwide are low birth weight (LBW), representing more than 20 million births a year, the great majority of them reported in low- and middle-income countries.[7] LBW is also a major contributor to both neonatal and child mortality.[8]
Hypothermia is associated with neonatal morbidity and mortality in high and low-resource settings.[9-13] Thermal care is a critical and essential component of newborn care in low-resource settings where supportive care is limited.[9-13] Appropriate interventions include warm rooms, skin-to-skin care, protective clothes and breastfeeding.[14]
Kangaroo mother care (KMC) is a low-cost intervention that includes prolonged skin-to-skin contact (SSC) between mother and newborn, exclusive breastfeeding, early discharge from the health facility, and close follow-up at home.[15] KMC is strongly recommended because it may prevent many complications associated with preterm birth and may also provide benefits to full-term newborns.[16,17] The World Health Organization (WHO) guidelines recommend that during KMC the baby's head be covered with a hat/cap to prevent thermal dispersion, [18] but this practice is not consistently followed in low-resource settings. Previous studies suggested that the application of woolen hats may reduce the neonatal heat loss immediately after birth, but its effect
during the early postnatal period remains to be defined.[19,20] It is unknown whether covering the head of the neonate with a hat/cap during KMC may help temperature maintenance during the early postnatal period. On the other hand, excessive covering of the neonates can result in hyperthermia, which is dangerous and should be avoided.[21,22] Therefore, the aim of the present study was to evaluate the effectiveness and the safety of a woolen cap in maintaining LBWI in normal thermal range in during KMC.

Methods

Study design
This was a multicenter, multi-country, double arm, unblinded, and randomized clinical trial evaluating the effectiveness and the safety of a woolen cap in maintaining normothermia in LBWI during KMC.[23]
Settings
The study was carried out at the Central Hospital of Beira (Mozambique), the St. Luke Wolisso Hospital (Ethiopia) and the Aber Hospital (Uganda).[24] In the participating hospitals, KMC represents a standard of care, but the heads of the babies often remain uncovered.
Ethics

Ethics clearance was sought and received by the local ethics committees of the participating centers.[23] Informed written consent was signed by a parent prior to starting KMC treatment. A senior investigator was available at all times to discuss concerns raised by parents or clinicians during the course of the trial.
Patients
After obtaining written parental consent, all infants with a birth weight below 2500 grams and who were candidates for KMC based on WHO guidelines were randomly assigned, with a 1:1 ratio, to KMC with a woolen cap (intervention arm: CAP) or to KMC without a woolen cap (control arm: NOCAP).[23] Newborns with major congenital malformations, twins or without parental consent were excluded from the study.
Rivista Italiana on line "LA CARE" Volume 11, Numero 1-2, anno 2018
41
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